Aim:

The aim of this systematic review was to determine if the nutrients in mixed concentrated fruit and vegetable (FV) products are bioavailable and if any of the cardiovascular health benefits attributed to eating fresh produce can also be obtained through supplementation.  

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Methods:

Researchers combed through 2 databases of scientific studies — MEDLINE and EMBASE — to identify any investigating the effects of FV products on cardiovascular health.  

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Results:

None of the studies reported any adverse effects of taking FV products. Positive outcomes reported included: 

• Significantly increased blood levels of folate and major antioxidant provitamins and vitamins found in fruits and vegetables, namely: beta carotene, vitamin C, and vitamin E 
• Significantly lowered levels of oxidative stress, as demonstrated by reduced markers of protein, lipid, and DNA oxidation 
• Significantly reduced homocysteine levels 
• Promising outcomes on markers of inflammation, immunity, and endothelial function  

These results indicate the nutrients in FV products are bioavailable and that FV products may positively impact multiple markers of cardiovascular health. 

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Conclusion:

Overall, the studies conducted to date indicate that the FV concentrates are effective in significantly improving circulating concentrations of antioxidant vitamins, provitamins, and folate and decreasing markers of oxidative stress. There are also data indicating that FV concentrates may decrease inflammatory biomarkers and improve immune function. While these supplements are not meant to replace healthy and well-balanced diet rich in fruits and vegetables, they may provide a useful means by which individuals can improve intake of FV bioactives.

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PubMed link:

https://pubmed.ncbi.nlm.nih.gov/22081614/